Two people confirmed dead after an unresponsive U.S. private plane crashed off the east coast of Jamaica on Friday, authorities said.

Jamaican Defense Force Maj. Basil Jarrett said that the plane, carrying Larry Glazer, a New York real estate executive, and his wife, Jane Glazer, crashed 14 miles northeast of Port Antonio. Both people on board died, Glazer’s son confirmed.

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Search and rescue teams, including Jamaican military helicopter, were sent off to the crash site. The United States Coast Guard also joined the search operation with an HC-130 Hercules airplane and a helicopter.

"At this time, no signs of aircraft or wreckage have been located," a U.S. Coast Guard spokesman said.

The Socata TBM700, a high-performance single-engine turboprop, took off at 8:45 a.m. EDT from Rochester and was bound for Naples, Florida.

The U.S. Federal Aviation Administration (FAA) said that the aircraft stopped responding to traffic controllers at 10 a.m. EDT and continued to fly for several hours until it crashed into the Caribbean Sea near Jamaica.

According to the North American Aerospace Defense Command (NORAD) spokesman Preston Schlachter, two U.S. fighter jets rushed up to shadow the plane after the pilot failed to respond. A pair of F-15s followed the aircraft until it reached the Cuban airspace.

The fighter jet pilots saw the pilot of the Socata TBM700 unconscious and slumped over. The pilot may have suffered "hypoxia," a rare condition caused by oxygen deprivation which left everyone on board unconscious, NORAD told the reporters.

TagsU.S. plane, crash, Jamaica, Larry Glazer, death